Casey Crime Investigation Unit detectives and Critical Incident Response Team officers arrested a 39-year-old man following a stabbing in Narre Warren North on 2 October.
Police executed a warrant at a Narre Warren address this morning and arrested a man about 10.30am.
It comes after a large scale police hunt last week, after an elderly couple were stabbed with a sharp-edged weapon near Troups Creek Retarding Basin on Sunday 2 October.
Investigators have been told a man and a woman were walking along a track near Drysdale Avenue and Settlers Hill Place when they were approached by an unknown man about 6.50am.
It is alleged the man attacked the pair with a sharp-edged weapon before running from the scene.
A 70-year-old Narre Warren man and a 57-year-old Pakenham woman were taken to hospital with non-life-threatening injuries and have since been released.
The alleged offender was reportedly sighted in the same area several days later, causing police to ramp up their search for him.
He is currently assisting police with their enquiries.