Kangan Drive in Berwick will be closed in both directions at the Clyde Road intersection nightly until Friday, 12 September.
This will run from 8pm to 5am each night, as part of the Clyde Road Upgrade works.
Detour can be accessed through O’Shea Road and Soldiers Road to the south, or the Princes Highway and Bryn Mawr Boulevard to the north.
Also announced earlier, Thompsons Road is closed in both directions between Berwick-Cranbourne Road and Matterhorn Drive until late December for the South-Eastern Roads Upgrade project.
The detour for this can be accessed through Bells Road and Hardys Road, or Soldiers Road and Grices Road.
For real-time information, see VicTraffic at traffic.transport.vic.gov.au.